Gly-Gly-Phe-Gly-NH-O-CO-Exatecan (hydrochloride)

MedChem Express

Gly-Gly-Phe-Gly-NH-O-CO-Exatecan (hydrochloride)

5

Research Use Only

99.88

C42H46ClFN8O10

877.31

Gly-Gly-Phe-Gly-NH-O-CO-Exatecan, as a drug-linker conjugate composed of linker Gly-Gly-Phe-Gly-NH-O-CO and Exatecan, can be used to prepare antibody conjugate drugs. Exatecan is a DNA topoisomerase I inhibitor that can be used in cancer research[1][2].

CC1=C(F)C=C2C3=C1CC[C@H](NC(COCNC(CNC([C@H](CC4=CC=CC=C4)NC(CNC(CN)=O)=O)=O)=O)=O)C3=C5C(C(N6C5)=CC([C@@](O)(CC)C(OC7)=O)=C7C6=O)=N2.[H]Cl

-20°C

41115800