Glypican 1 antibody [N3C3]
GTX104557
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetGPC1
Overview
- SupplierGeneTex
- Product NameGlypican 1 antibody [N3C3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. FACS: 1:50-1:200. IP: 1:100-1:500. ELISA: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.71 mg/ml
- ConjugateUnconjugated
- Gene ID2817
- Target nameGPC1
- Target descriptionglypican 1
- Target synonymsepididymis secretory sperm binding protein; glypican; glypican proteoglycan 1; glypican-1
- HostRabbit
- IsotypeIgG
- Protein IDP35052
- Protein NameGlypican-1
- Scientific DescriptionCell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- A glypican-1-targeted antibody-drug conjugate exhibits potent tumor growth inhibition in glypican-1-positive pancreatic cancer and esophageal squamous cell carcinoma. Munekage E et al., 2021 Sep, NeoplasiaRead more
- Increased secretion of VEGF-C from SiO2-induced pulmonary macrophages promotes lymphangiogenesis through the Src/eNOS pathway in silicosis. Zhang J et al., 2021 Apr 29, Ecotoxicol Environ SafRead more
- Inhibition of glypican-1 expression induces an activated fibroblast phenotype in a human bone marrow-derived stromal cell-line. Kaur SP et al., 2021 Apr 29, Sci RepRead more
- Oncogenic and Non-Malignant Pancreatic Exosome Cargo Reveal Distinct Expression of Oncogenic and Prognostic Factors Involved in Tumor Invasion and Metastasis. Emmanouilidi A et al., 2019 Apr, ProteomicsRead more
- Abnormal ER quality control of neural GPI-anchored proteins via dysfunction in ER export processing in the frontal cortex of elderly subjects with schizophrenia. Kim P et al., 2019 Jan 16, Transl PsychiatryRead more
- Elevated glypican-1 expression is associated with an unfavorable prognosis in pancreatic ductal adenocarcinoma. Lu H et al., 2017 Jun, Cancer MedRead more
- Sphingosine-1-phosphate improves endothelialization with reduction of thrombosis in recellularized human umbilical vein graft by inhibiting syndecan-1 shedding in vitro. Hsia K et al., 2017 Mar 15, Acta BiomaterRead more
- alpha3 Chains of type V collagen regulate breast tumour growth via glypican-1. Huang G et al., 2017 Jan 19, Nat CommunRead more
- Differential expression of glypican-1 in ameloblastoma variants. Bologna-Molina R et al., 2015 Feb, Appl Immunohistochem Mol MorpholRead more