Glypican-3/GPC3, Human (HEK293, His)

MedChem Express

Glypican-3/GPC3, Human (HEK293, His)

10

Research Use Only

98.0

GPC3

glypican 3

DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1, glypican-3, glypican proteoglycan 3, heparan sulphate proteoglycan, intestinal protein OCI-5, secreted glypican-3

Glypican-3

The Glypican-3 (GPC3) protein is a cell surface proteoglycan that plays complex regulatory roles in key signaling pathways critical to developmental processes. Through its GPI anchoring, GPC3 negatively regulates the Hedgehog signaling pathway by competing with the Hedgehog receptor PTC1 for binding to Hedgehog protein, leading to complex internalization and subsequent lysosomal degradation. Glypican-3/GPC3 Protein, Human (HEK293, His) is the recombinant human-derived Glypican-3/GPC3 protein, expressed by HEK293 , with C-His labeled tag.

-20°C

41116100

Human