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GM-CSF antibody [MP1-22E9]

Name: GM-CSF antibody [MP1-22E9]
SKU: GTX13788_G10
Availability: BackOrder

GTX13788

ApplicationsFlow Cytometry, Western Blot, ELISA, ELISpot Assay, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Neutralisation/Blocking

Product group Antibodies

ReactivityMouse

TargetCSF2

Overview

Supplier
GeneTex
Product Name
GM-CSF antibody [MP1-22E9]
Delivery Days Customer
9
Application Supplier Note
WB: . *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Flow Cytometry, Western Blot, ELISA, ELISpot Assay, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Neutralisation/Blocking
Certification
Research Use Only
Clonality
Monoclonal
Clone ID
MP1-22E9
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID1437
Target name
CSF2
Target description
colony stimulating factor 2
Target synonyms
CSF, GMCSF, granulocyte-macrophage colony-stimulating factor, colony stimulating factor 2 (granulocyte-macrophage), granulocyte macrophage-colony stimulating factor, molgramostim, molgramostin, sargramostim
Host
Rat
Isotype
IgG2a
Protein IDP04141
Protein Name
Granulocyte-macrophage colony-stimulating factor
Scientific Description
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq, Jul 2008]
Reactivity
Mouse
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Vaillant L, Oster P, McMillan B, et al. GM-CSF is key in the efficacy of vaccine-induced reduction of Helicobacter pylori infection. Helicobacter. 2022,27(2):e12875. doi: 10.1111/hel.12875
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Regan-Komito D, Swann JW, Demetriou P, et al. GM-CSF drives dysregulated hematopoietic stem cell activity and pathogenic extramedullary myelopoiesis in experimental spondyloarthritis. Nat Commun. 2020,11(1):155. doi: 10.1038/s41467-019-13853-4
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Cook AD, Pobjoy J, Steidl S, et al. Granulocyte-macrophage colony-stimulating factor is a key mediator in experimental osteoarthritis pain and disease development. Arthritis Res Ther. 2012,14(5):R199. doi: 10.1186/ar4037
Read this paper