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GMP BDNF, Human

HY-P7116G
MedChem Express
Protein IDP23560
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    MedChem Express
  • Product Name
    GMP BDNF, Human
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Gene ID627
  • Target name
    BDNF
  • Target description
    brain derived neurotrophic factor
  • Target synonyms
    abrineurin; ANON2; brain-derived neurotrophic factor; BULN2; neurotrophin
  • Protein IDP23560
  • Protein Name
    Brain-derived neurotrophic factor
  • Scientific Description
    Brain Derived Neurotrophic Factor (BDNF) is a neurotrophin that belongs to NGF-beta family. BDNF can bind to its high affinity receptor TrkB and activates signal transduction cascades (IRS1/2, PI3K, Akt)[1]. BDNF can also bind to the p75NTR, but the affinity for the p75NTR receptor is lower than for TrkB[2]. BDNF is a neurotransmitter modulator, and is vital in maturation, survival and differentiation of neuronal populations during development. BDNF also participates in neuronal plasticity, which is essential for learning and memory. BDNF is widely expressed in the CNS[1]. GMP BDNF Protein, Human is a recombinant human BDNF (H129-R247) without tag, which is produced in E.coli.
  • UNSPSC
    41116100