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GNAQ antibody

GTX104544
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetGNAQ
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Overview

  • Supplier
    GeneTex
  • Product Name
    GNAQ antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2776
  • Target name
    GNAQ
  • Target description
    G protein subunit alpha q
  • Target synonyms
    CMAL, CMC1, G-ALPHA-q, GAQ, SWS, guanine nucleotide-binding protein G(q) subunit alpha, epididymis secretory sperm binding protein, guanine nucleotide binding protein (G protein), q polypeptide, guanine nucleotide-binding protein alpha-q
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP50148
  • Protein Name
    Guanine nucleotide-binding protein G(q) subunit alpha
  • Scientific Description
    Guanine nucleotide-binding proteins are a family of heterotrimeric proteins that couple cell surface, 7-transmembrane domain receptors to intracellular signaling pathways. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. The G protein alpha and beta-gamma subunits are capable of regulating various cellular effectors. Activation is terminated by a GTPase intrinsic to the G-alpha subunit. G-alpha-q is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C-beta (MIM 600230).[supplied by OMIM]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Higa-Nakamine S, Maeda N, Toku S, et al. Involvement of Protein Kinase D1 in Signal Transduction from the Protein Kinase C Pathway to the Tyrosine Kinase Pathway in Response to Gonadotropin-releasing Hormone. J Biol Chem. 2015,290(43):25974-85. doi: 10.1074/jbc.M115.681700
    Read this paper