GNE-0723 [1883518-31-7]

MedChem Express

GNE-0723 [1883518-31-7]

5

1883518-31-7

Research Use Only

98.74

C16H8ClF6N5OS

467.78

GNE-0723 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 21 nM for GluN2A, 7.4 and 6.2 microM for GluN2C and GluN2D, respectively[1].

N#C[C@H]1[C@H](C2=C(C(F)(F)F)SC3=NC(CN4N=C(C(F)(F)F)C=C4Cl)=CC(N32)=O)C1

-20°C, 3 years; 4°C, 2 years (Powder)

12352200