GNE-781

Biorbyt

GNE-781 [1936422-33-1]

10

1936422-33-1

Research Use Only

C27H33F2N7O2

525.605

GNE-781 is a potent, selective, non-CNS penetrant, orally active CBP/p300 bromodomain inhibitor with IC50 of 0.94/1.2 nM in TR-FRET assays.

FC(C1C(C2C=NN(C)C=2)=CC2CCCN(C=2C=1)C1C2CN(C(NC)=O)CCC=2N(C2CCOCC2)N=1)F

12352200