GNE-886 [2101957-05-3]

MedChem Express

GNE-886 [2101957-05-3]

10

2101957-05-3

Research Use Only

99.81

C28H30N6O3

498.58

GNE-886 (Compound 21) is a potent and selective inhibitor of Cat eye syndrome chromosome region candidate 2 bromodomain (CECR2) (BRD) with an IC50 value of 0.016 microM and an EC50 value of 370 nM. GNE-886 also inhibits BRD9 with an IC50 value of 1.6 microM[1].

O=C(C1=CN(CC=C)C(C2=C1C=CN2)=O)N(C3CCN(C4=NC=NC(C5=CC=CC(OC)=C5)=C4)CC3)C

2°C to 8°C

12352200