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ProductsBack/GNF-5837 [1033769-28-6]

GNF-5837 [1033769-28-6]

Research Use Only
HY-13491
MedChem Express
CAS Number1033769-28-6
DownloadMSDS
Product group Chemicals
Estimated Purity99.65
Molecular Weight535.49
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Overview

  • Supplier
    MedChem Express
  • Product Name
    GNF-5837 [1033769-28-6]
  • Delivery Days Customer
    10
  • CAS Number
    1033769-28-6
  • Certification
    Research Use Only
  • Estimated Purity
    99.65
  • Molecular Formula
    C28H21F4N5O2
  • Molecular Weight
    535.49
  • Scientific Description
    GNF-5837 is a potent, selective, and orally bioavailable pan-tropomyosin receptor kinase (TRK) inhibitor which display antiproliferative effects in cellular Ba/F3 assays ( IC50 values of 7 nM, 9 nM and 11 nM for cells containing the fusion proteins Tel-TrkC, Tel-TrkB and Tel-TrkA, respectively) [1].
  • SMILES
    O=C(NC1=CC(C(F)(F)F)=CC=C1F)NC2=CC=C(C)C(NC3=CC(NC/4=O)=C(C=C3)C4=C\C5=CC=CN5)=C2
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200