GNF351 [1227634-69-6]

TargetMol Chemicals

GNF351 [1227634-69-6]

4

1227634-69-6

Chemical

Research Use Only

GNF351

99.04%

C24H25N7

411.5

GNF351 is a full antagonist of the aryl hydrocarbon receptor (AHR)with the capacity to inhibit both DRE-dependent and -independent activity. GNF351 is minimal toxicity in mouse or human keratinocytes. GNF351 competes with a photoaffinity AHR ligand for binding to the AHR (IC50: 62 nM).

3 years

CC(C)n1cnc2c(NCCc3c[nH]c4ccccc34)nc(nc12)-c1cncc(C)c1

-20°C

12352200