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Goat anti-LRRK2 / PARK8 (near C Terminus)

Name: Goat anti-LRRK2 / PARK8 (near C Terminus)
SKU: EB06550_100ug_E85
Availability: BackOrder

EB06550

ApplicationsImmunoFluorescence, ELISA

Product group Antibodies

ReactivityHuman

TargetLRRK2

Overview

Supplier
Everest Biotech
Product Name
Goat anti-LRRK2 / PARK8 (near C Terminus)
Delivery Days Customer
7
Application Supplier Note
Immunofluorescence: Strong expression of the protein seen in the vesicles of A431 cells and in the vesicles and nuclei of A549 cells. Recommended concentration: 10microg/ml.
Applications
ImmunoFluorescence, ELISA
Applications Supplier
Pep-ELISA, IF
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.5 mg/ml
Gene ID120892
Target name
LRRK2
Target description
leucine rich repeat kinase 2
Target synonyms
AURA17, DARDARIN, PARK8, RIPK7, ROCO2, leucine-rich repeat serine/threonine-protein kinase 2, augmented in rheumatoid arthritis 17
Host
Goat
Scientific Description
RefSeq number(s): NP_940980.3. Purification: Antigen affinity purified. Names and symbols: LRRK2; PARK8; ROCO2; FLJ45829; DKFZp434H2111; leucine-rich repeat kinase 2; dardarin; Parkinson disease (autosomal dominant) 8; AURA17; DARDARIN; RIPK7; augmented in rheumatoid arthritis 17
Reactivity
Human
Reactivity Supplier
Human
Storage Instruction
-20°C
UNSPSC
12352203

Sharma S, Bandopadhyay R, Lashley T, et al. LRRK2 expression in idiopathic and G2019S positive Parkinson's disease subjects: a morphological and quantitative study. Neuropathol Appl Neurobiol. 2011,37(7):777-90. doi: 10.1111/j.1365-2990.2011.01187.x
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Alegre-Abarrategui J, Christian H, Lufino MM, et al. LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model. Hum Mol Genet. 2009,18(21):4022-34. doi: 10.1093/hmg/ddp346
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Alegre-Abarrategui J, Ansorge O, Esiri M, et al. LRRK2 is a component of granular alpha-synuclein pathology in the brainstem of Parkinson's disease. Neuropathol Appl Neurobiol. 2008,34(3):272-83.
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