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ProductsBack/Goat anti-Melanophilin (mouse)

Goat anti-Melanophilin (mouse)

Research Use Only
EB05444
Everest Biotech
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
Product group Antibodies
ReactivityMouse, Rat
TargetMlph
100 ug
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Overview

  • Supplier
    Everest Biotech
  • Product Name
    Goat anti-Melanophilin (mouse) Antibody
  • Delivery Days Customer
    5
  • Application Supplier Note
    Immunofluorescence: Successfully used at 0.5ug/ml to stain mouse melanocytes. This antibody has been successfully used in IF on Mouse: Figueiredo AC et al., J Biol Chem. 2008 Aug 22;283(34):23209-16. PMID:18559336. GST-pull down assay: See publication Figueiredo AC et al., J Biol Chem. 2008 Aug 22;283(34):23209-16. (PMID:18559336).
  • Applications
    ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
  • Applications Supplier
    Pep-ELISA, WB, ICC, IF, GST-pull down
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.5 mg/ml
  • Gene ID171531
  • Target name
    Mlph
  • Target description
    melanophilin
  • Target synonyms
    2210418F23Rik; 5031433I09Rik; AW228792; D1Wsu84; D1Wsu84e; exophilin-3; l(1)-3Rk; l1Rk3; leaden protein; ln; melanophilin; Sla; Slac-2a; slaC2-a; slp homolog lacking C2 domains a; synaptotagmin-like protein 2a
  • Host
    Goat
  • Scientific Description
    RefSeq number(s): NP_443748.2. GeneIDs all Nonhuman: 171531 (mouse); 316620 (rat);. Purification: Antigen affinity purified. Names and symbols: 2210418F23Rik; melanophilin; Mlph; ln; l1Rk3; Slac-2a; D1Wsu84e; l(1)-3Rk; 5031433I09Rik; leaden; AW228792; OTTMUSP00000025451
  • Reactivity
    Mouse, Rat
  • Reactivity Supplier
    Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203

References

  • Nucleotide exchange factor Rab3GEP requires DENN and non-DENN elements for activation and targeting of Rab27a. Sanza P et al., 2019 Apr 30, J Cell Sci
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  • Distinct and opposing roles for Rab27a/Mlph/MyoVa and Rab27b/Munc13-4 in mast cell secretion. Singh RK et al., 2013 Feb, FEBS J
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  • Rab3GEP is the non-redundant guanine nucleotide exchange factor for Rab27a in melanocytes. Figueiredo AC et al., 2008 Aug 22, J Biol Chem
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  • A coiled-coil domain of melanophilin is essential for Myosin Va recruitment and melanosome transport in melanocytes. Hume AN et al., 2006 Nov, Mol Biol Cell
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