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Goat anti-Melanophilin (mouse) Antibody

Name: Goat anti-Melanophilin (mouse) Antibody
SKU: EB05444_100ug_E85
Availability: BackOrder

EB05444

ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry

Product group Antibodies

ReactivityMouse, Rat

TargetMlph

Overview

Supplier
Everest Biotech
Product Name
Goat anti-Melanophilin (mouse) Antibody
Delivery Days Customer
5
Application Supplier Note
Immunofluorescence: Successfully used at 0.5ug/ml to stain mouse melanocytes. This antibody has been successfully used in IF on Mouse: Figueiredo AC et al., J Biol Chem. 2008 Aug 22;283(34):23209-16. PMID:18559336. GST-pull down assay: See publication Figueiredo AC et al., J Biol Chem. 2008 Aug 22;283(34):23209-16. (PMID:18559336).
Applications
ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
Applications Supplier
Pep-ELISA, WB, ICC, IF, GST-pull down
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.5 mg/ml
Gene ID171531
Target name
Mlph
Target description
melanophilin
Target synonyms
2210418F23Rik, 5031433I09Rik, D1Wsu84e, Slac-2a, l(1)-3Rk, l1Rk3, ln, melanophilin, exophilin-3, leaden protein, slaC2-a, slp homolog lacking C2 domains a, synaptotagmin-like protein 2a
Host
Goat
Scientific Description
RefSeq number(s): NP_443748.2. GeneIDs all Nonhuman: 171531 (mouse); 316620 (rat);. Purification: Antigen affinity purified. Names and symbols: 2210418F23Rik; melanophilin; Mlph; ln; l1Rk3; Slac-2a; D1Wsu84e; l(1)-3Rk; 5031433I09Rik; leaden; AW228792; OTTMUSP00000025451
Reactivity
Mouse, Rat
Reactivity Supplier
Mouse, Rat
Storage Instruction
-20°C
UNSPSC
12352203

Sanzà P, Evans RD, Briggs DA, et al. Nucleotide exchange factor Rab3GEP requires DENN and non-DENN elements for activation and targeting of Rab27a. J Cell Sci. 2019,132(9). doi: 10.1242/jcs.212035
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Singh RK, Mizuno K, Wasmeier C, et al. Distinct and opposing roles for Rab27a/Mlph/MyoVa and Rab27b/Munc13-4 in mast cell secretion. FEBS J. 2013,280(3):892-903. doi: 10.1111/febs.12081
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Figueiredo AC, Wasmeier C, Tarafder AK, et al. Rab3GEP is the non-redundant guanine nucleotide exchange factor for Rab27a in melanocytes. J Biol Chem. 2008,283(34):23209-16. doi: 10.1074/jbc.M804134200
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Hume AN, Tarafder AK, Ramalho JS, et al. A coiled-coil domain of melanophilin is essential for Myosin Va recruitment and melanosome transport in melanocytes. Mol Biol Cell. 2006,17(11):4720-35.
Read this paper