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Goat anti-PPPDE1 / PNAS4 Antibody

Name: Goat anti-PPPDE1 / PNAS4 Antibody
SKU: EB10317_100ug_E85
Availability: BackOrder

EB10317

ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry

Product group Antibodies

ReactivityBovine, Canine, Human, Mouse, Porcine, Rat

TargetDESI2

Overview

Supplier
Everest Biotech
Product Name
Goat anti-PPPDE1 / PNAS4 Antibody
Delivery Days Customer
5
Application Supplier Note
Purchase the +ve control! The transfected lysate used to QC this product is available for sale. Please email sales@everestbiotech.com to request datasheet, pricing and delivery information.
Applications
Western Blot, ELISA, ImmunoHistoChemistry
Applications Supplier
Pep-ELISA, WB-Trf, IHC
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.5 mg/ml
Gene ID51029
Target name
DESI2
Target description
desumoylating isopeptidase 2
Target synonyms
C1orf121, CGI-146, DESI, DESI1, DeSI-2, FAM152A, PNAS-4, PPPDE1, deubiquitinase DESI2, PPPDE peptidase domain-containing protein 1, S-depalmitoylase DESI2, desumoylating isopeptidase 1, family with sequence similarity 152, member A, palmitoyl protein thioesterase DESI2
Host
Goat
Scientific Description
RefSeq number(s): NP_057160.2. GeneIDs all Nonhuman: 78825 (mouse); 289277 (rat);. Purification: Antigen affinity purified. Names and symbols: PPPDE1; PPPDE peptidase domain containing 1; C1orf121; CGI-146; FAM152A; FLJ21998; PNAS-4; family with sequence similarity 152, member A
Reactivity
Bovine, Canine, Human, Mouse, Porcine, Rat
Reactivity Supplier
Human, Mouse, Rat, Dog, Cow, Pig
Storage Instruction
-20°C
UNSPSC
12352203

Yan H, Guo W, Li K, et al. Combination of DESI2 and endostatin gene therapy significantly improves antitumor efficacy by accumulating DNA lesions, inducing apoptosis and inhibiting angiogenesis. Exp Cell Res. 2018,371(1):50-62. doi: 10.1016/j.yexcr.2018.07.040
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Lin C, Yan H, Yang J, et al. Combination of DESI2 and IP10 gene therapy significantly improves therapeutic efficacy against murine carcinoma. Oncotarget. 2017,8(34):56281-56295. doi: 10.18632/oncotarget.17623
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Yuan Z, Guo W, Yang J, et al. PNAS-4, an Early DNA Damage Response Gene, Induces S Phase Arrest and Apoptosis by Activating Checkpoint Kinases in Lung Cancer Cells. J Biol Chem. 2015,290(24):14927-44. doi: 10.1074/jbc.M115.658419
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Li L, Chen DB, Lin C, et al. hPNAS-4 inhibits proliferation through S phase arrest and apoptosis: underlying action mechanism in ovarian cancer cells. Apoptosis. 2013,18(4):467-79. doi: 10.1007/s10495-012-0797-z
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Zeng H, Yuan Z, Zhu H, et al. Expression of hPNAS-4 radiosensitizes Lewis lung cancer. Int J Radiat Oncol Biol Phys. 2012,84(4):e533-40. doi: 10.1016/j.ijrobp.2012.06.028
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