Bio-Connect

Goat anti-PPPDE1 / PNAS4

EB10317
Everest Biotech
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityBovine, Canine, Human, Mouse, Porcine, Rat
TargetDESI2
100 ug
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Overview

  • Supplier
    Everest Biotech
  • Product Name
    Goat anti-PPPDE1 / PNAS4 Antibody
  • Delivery Days Customer
    5
  • Application Supplier Note
    Purchase the +ve control! The transfected lysate used to QC this product is available for sale. Please email sales@everestbiotech.com to request datasheet, pricing and delivery information.
  • Applications
    Western Blot, ELISA, ImmunoHistoChemistry
  • Applications Supplier
    Pep-ELISA, WB-Trf, IHC
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.5 mg/ml
  • Gene ID51029
  • Target name
    DESI2
  • Target description
    desumoylating isopeptidase 2
  • Target synonyms
    C1orf121; CGI-146; DESI; DESI1; DeSI-2; desumoylating isopeptidase 1; deubiquitinase DESI2; FAM152A; family with sequence similarity 152, member A; PNAS-4; PPPDE peptidase domain-containing protein 1; PPPDE1
  • Host
    Goat
  • Scientific Description
    RefSeq number(s): NP_057160.2. GeneIDs all Nonhuman: 78825 (mouse); 289277 (rat);. Purification: Antigen affinity purified. Names and symbols: PPPDE1; PPPDE peptidase domain containing 1; C1orf121; CGI-146; FAM152A; FLJ21998; PNAS-4; family with sequence similarity 152, member A
  • Reactivity
    Bovine, Canine, Human, Mouse, Porcine, Rat
  • Reactivity Supplier
    Human, Mouse, Rat, Dog, Cow, Pig
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203

References

  • Combination of DESI2 and endostatin gene therapy significantly improves antitumor efficacy by accumulating DNA lesions, inducing apoptosis and inhibiting angiogenesis. Yan H et al., 2018 Oct 1, Exp Cell Res
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  • Combination of DESI2 and IP10 gene therapy significantly improves therapeutic efficacy against murine carcinoma. Lin C et al., 2017 Aug 22, Oncotarget
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  • PNAS-4, an Early DNA Damage Response Gene, Induces S Phase Arrest and Apoptosis by Activating Checkpoint Kinases in Lung Cancer Cells. Yuan Z et al., 2015 Jun 12, J Biol Chem
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  • hPNAS-4 inhibits proliferation through S phase arrest and apoptosis: underlying action mechanism in ovarian cancer cells. Li L et al., 2013 Apr, Apoptosis
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  • Expression of hPNAS-4 radiosensitizes Lewis lung cancer. Zeng H et al., 2012 Nov 15, Int J Radiat Oncol Biol Phys
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