Gomisin N [69176-52-9]

MedChem Express

Gomisin N [69176-52-9]

9

69176-52-9

Research Use Only

99.94

C23H28O6

400.46

Gomisin N is an orally active lignan compound. Gomisin N can be isolated from Schisandra chinensis. Gomisin N induces Apoptosis in a variety of cells. Gomisin N activates AMPK, Akt, MAPK/ERK, Nrf2, caspase-3 and PARP-1. Gomisin N inhibits GSK3beta, nitric oxide (NO), and proinflammatory cytokines (IL-1beta, IL-6, TNF-alpha). Gomisin N has anti-inflammatory, antioxidant, anti-obesity, anti-diabetic, and anti-melanogenesis activities. Gomisin N has anti-tumor activity against cervical cancer and liver cancer. Gomisin N improves Alzheimers disease[1][2][3][4][5][6][7][8][9][10].

COC1=C2OCOC2=CC(C[C@@H]3C)=C1C(C(C[C@H]3C)=CC(OC)=C4OC)=C4OC

2°C to 8°C

12352200