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Gossypetin [489-35-0]

Research Use Only
TN1711
TargetMol Chemicals
CAS Number489-35-0
Product group Chemicals
Molecular Weight318.24
Price on request
Packing Size
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Gossypetin [489-35-0]
  • Delivery Days Customer
    9
  • CAS Number
    489-35-0
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Gossypetin
  • Molecular Formula
    C15H10O8
  • Molecular Weight
    318.24
  • Scientific Description
    Gossypetin, a hexahydroxylated flavonoid extractable from Rhodiola rosea Linn. is a potent MKK3 and MKK6 inhibitor that strongly attenuates the MKK3/6-p38 signaling pathway.Gossypetin exhibits antimutagenic, antiatherosclerotic, antioxidant, as well as cytoprotective and antimicrobial effects.It inhibits bone resorption by downregulating lysosomal caspase K activity and inducing autophagy-associated proteins in actin ring osteoclasts. Gossypetin has anti-mutagenic, anti-atherosclerotic, anti-oxidant, cytoprotective and antibacterial effects, and it inhibits bone resorption by down-regulating lysosomal caspase K activity and by inducing autophagy-associated protein in actin ring osteoblasts.
  • Shelf life instruction
    3 years
  • SMILES
    Oc1ccc(cc1O)-c1oc2c(O)c(O)cc(O)c2c(=O)c1O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Xie X, et al. Gossypetin is a novel MKK3 and MKK6 inhibitor that suppresses esophageal cancer growth in vitro and in vivo. Cancer Lett. 2019;442:126-136.
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