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Gossypetin [489-35-0]
TN1711
Overview
- SupplierTargetMol Chemicals
- Product NameGossypetin [489-35-0]
- Delivery Days Customer9
- CAS Number489-35-0
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameGossypetin
- Molecular FormulaC15H10O8
- Molecular Weight318.24
- Scientific DescriptionGossypetin, a hexahydroxylated flavonoid extractable from Rhodiola rosea Linn. is a potent MKK3 and MKK6 inhibitor that strongly attenuates the MKK3/6-p38 signaling pathway.Gossypetin exhibits antimutagenic, antiatherosclerotic, antioxidant, as well as cytoprotective and antimicrobial effects.It inhibits bone resorption by downregulating lysosomal caspase K activity and inducing autophagy-associated proteins in actin ring osteoclasts. Gossypetin has anti-mutagenic, anti-atherosclerotic, anti-oxidant, cytoprotective and antibacterial effects, and it inhibits bone resorption by down-regulating lysosomal caspase K activity and by inducing autophagy-associated protein in actin ring osteoblasts.
- Shelf life instruction3 years
- SMILESOc1ccc(cc1O)-c1oc2c(O)c(O)cc(O)c2c(=O)c1O
- Storage Instruction-20°C
- UNSPSC12352200
References
- Xie X, et al. Gossypetin is a novel MKK3 and MKK6 inhibitor that suppresses esophageal cancer growth in vitro and in vivo. Cancer Lett. 2019;442:126-136.Read more