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GPAA1 antibody

GTX115131
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetGPAA1
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Overview

  • Supplier
    GeneTex
  • Product Name
    GPAA1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.76 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID8733
  • Target name
    GPAA1
  • Target description
    glycosylphosphatidylinositol anchor attachment 1
  • Target synonyms
    GAA1, GPIBD15, hGAA1, GPI-anchor transamidase component GPAA1, GAA1 protein homolog, GPAA1P anchor attachment protein 1 homolog, GPI anchor attachment protein 1, GPI transamidase subunit, anchor attachment protein 1 (Gaa1p, yeast) homolog, glycophosphatidylinositol anchor attachment 1, glycosylphosphatidylinositol anchor attachment 1 protein, glycosylphosphatidylinositol anchor attachment protein 1 homolog
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO43292
  • Protein Name
    GPI-anchor transamidase component GPAA1
  • Scientific Description
    Posttranslational glycosylphosphatidylinositol (GPI) anchor attachment serves as a general mechanism for linking proteins to the cell surface membrane. The protein encoded by this gene presumably functions in GPI anchoring at the GPI transfer step. The mRNA transcript is ubiquitously expressed in both fetal and adult tissues. The anchor attachment protein 1 contains an N-terminal signal sequence, 1 cAMP- and cGMP-dependent protein kinase phosphorylation site, 1 leucine zipper pattern, 2 potential N-glycosylation sites, and 8 putative transmembrane domains. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Sherman EJ, Mirabelli C, Tang VT, et al. Identification of cell type specific ACE2 modifiers by CRISPR screening. PLoS Pathog. 2022,18(3):e1010377. doi: 10.1371/journal.ppat.1010377
    Read this paper
  • Kim P, Scott MR, Meador-Woodruff JH. Abnormal ER quality control of neural GPI-anchored proteins via dysfunction in ER export processing in the frontal cortex of elderly subjects with schizophrenia. Transl Psychiatry. 2019,9(1):6. doi: 10.1038/s41398-018-0359-4
    Read this paper