GPBB antibody
GTX104291
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetPYGB
Overview
- SupplierGeneTex
- Product NameGPBB antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.36 mg/ml
- ConjugateUnconjugated
- Gene ID5834
- Target namePYGB
- Target descriptionglycogen phosphorylase B
- Target synonymsGPBB, glycogen phosphorylase, brain form, phosphorylase, glycogen; brain
- HostRabbit
- IsotypeIgG
- Protein IDP11216
- Protein NameGlycogen phosphorylase, brain form
- Scientific DescriptionThe protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Cooper ML, Pasini S, Lambert WS, et al. Redistribution of metabolic resources through astrocyte networks mitigates neurodegenerative stress. Proc Natl Acad Sci U S A. 2020,117(31):18810-18821. doi: 10.1073/pnas.2009425117Read this paper
- Geiszler PC, Ugun-Klusek A, Lawler K, et al. Dynamic metabolic patterns tracking neurodegeneration and gliosis following 26S proteasome dysfunction in mouse forebrain neurons. Sci Rep. 2018,8(1):4833. doi: 10.1038/s41598-018-23155-2Read this paper

