GPi688

MedChem Express

GPi688 [918902-32-6]

10

918902-32-6

Research Use Only

C19H18ClN3O4S

419.88

GPi688 is a potent and orally active glycogen phosphorylase (GPa) inhibitor with IC 50 s of 19 nM, 61 nM and 12 nM for human liver GPa, rat liver GPa and human skeletal muscle GPa, respectively [1] . GPi688 can inhibit glucagons-mediated glucose output in rat primary hepatocytes. GPi688 can be used for researching glucagon-mediated hyperglycaemia [2] .

O=C(C1=CC(C=C(Cl)S2)=C2N1)NC3C(N(C[C@@H](O)CO)C4=C(C=CC=C4)C3)=O

12352200