GPR120 Agonist 5 [1079821-35-4]

MedChem Express

GPR120 Agonist 5 [1079821-35-4]

5

1079821-35-4

Research Use Only

C23H24N2O3

376.45

GPR120 Agonist 5 (compound 12) is an agonist targeting GPR120 (EC50=1.2 microM). GPR120 Agonist 5 promotes the release of glucagon-like 1 (GLP-1) by binding to the GPR120 receptor, which in turn binds to its receptors on pancreatic beta cells, increasing insulin secretion and thereby lowering blood sugar levels. GPR120 Agonist 5 also helps reduce chronic low-grade inflammation, which plays an important role in the pathogenesis of obesity, insulin resistance, and type 2 diabetes. GPR120 Agonist 5 can be used to investigate the mechanism of action of GPR120 in metabolic and inflammatory diseases[1][2].

O=C(CCCC1=CC=C(C=C1)OCCN(C2=CC=CC=C2)C3=NC=CC=C3)O

12352200