GPR54 antibody
GTX100374
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Rat
TargetKISS1R
Overview
- SupplierGeneTex
- Product NameGPR54 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID84634
- Target nameKISS1R
- Target descriptionKISS1 receptor
- Target synonymsAXOR12; CPPB1; G protein-coupled receptor 54; GPR54; G-protein coupled receptor OT7T175; HH8; HOT7T175; hypogonadotropin-1; kiSS-1 receptor; KISS-1R; kisspeptins receptor; metastin receptor
- HostRabbit
- IsotypeIgG
- Protein IDQ969F8
- Protein NameKiSS-1 receptor
- Scientific DescriptionThe protein encoded by this gene is a galanin-like G protein-coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. The tissue distribution of the expressed gene suggests that it is involved in the regulation of endocrine function, and this is supported by the finding that this gene appears to play a role in the onset of puberty. Mutations in this gene have been associated with hypogonadotropic hypogonadism and central precocious puberty. [provided by RefSeq]
- ReactivityHuman, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Aging reduces kisspeptin receptor (GPR54) expression levels in the hypothalamus and extra-hypothalamic brain regions. Mattam U et al., 2021 Sep, Exp Ther MedRead more
- Kisspeptin regulation of genes involved in cell invasion and angiogenesis in first trimester human trophoblast cells. Francis VA et al., 2014, PLoS OneRead more