GPR87 -VLP, Human (HEK293)

MedChem Express

GPR87 -VLP, Human (HEK293)

5

Research Use Only

GPR87

G protein-coupled receptor 87

FKSG78; GPR95; G-protein coupled receptor 87; G-protein coupled receptor 95; KPG_002; orphan GPCR 87

G-protein coupled receptor 87

GPR87, a lysophosphatidic acid (LPA) receptor, crucially activates p53/TP53-dependent survival pathways in response to DNA damage. Its interaction with LPA plays a key role in mediating cellular responses to DNA damage, highlighting its significance in cell survival and DNA damage repair processes. GPR87 Protein-VLP, Human (HEK293) is the recombinant human-derived GPR87 protein, expressed by HEK293, with tag free.Formed in HEK293 cultures, these VLPs concentrate membrane proteins on the cell surface, producing high-concentration proteins ideal for immunization and antibody screening. Given the high immunogenicity of VLPs, the immunization protocol such as antigen dose, schedule, and adjuvant, requires optimization. It is not recommended for receptor-ligand interaction detection and SPR/BLI assay since there are other irrelevant membrane proteins of the host on the VLP envelope, and the receptor-ligand interaction will have strong background interference. High requirements for chips and experimental protocols are needed for SPR/BLI assays. If VLP control is required, it is recommended HY-P705433.

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