GPS1573 [2445822-54-6]

TargetMol Chemicals

GPS1573 [2445822-54-6]

9

Research Use Only

C86H138N28O14

1788.19

GPS1573 is a non-competitive antagonist of the melanocortin 2 receptor (MC2R) that blocks the ACTH-stimulated activity of MC2R in a dose-dependent manner (IC50=66 nM). Due to its high selectivity in antagonizing MC2R, GPS1573 is utilized for research in Cushings disease.

C([C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(N)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)=O)C(C)C)=O)C)=O)CCCCN)=O)=O)NC([C@@H](NC([C@H](NC(=O)[C@H]2N(C([C@H](CCCC)N)=O)CCC2)CC3=CC=CC=C3)=O)CCCNC(=N)N)=O)C=4C=5C(NC4)=CC=CC5

-20°C

12352200