GPSM2 Polyclonal Antibody

Reddot Biotech

GPSM2 Polyclonal Antibody

5

1.92 mg/ml

GPSM2

G protein signaling modulator 2

CMCS; DFNB82; G-protein signalling modulator 2 (AGS3-like, C. elegans); G-protein-signaling modulator 2; LGN; mosaic protein LGN; PINS

The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82). Alternative splicing results in multiple transcript variants.

-20°C

12352203