GPVI antagonist 3 [901654-94-2]

MedChem Express

GPVI antagonist 3 [901654-94-2]

10

901654-94-2

Research Use Only

C22H23N3O4

393.44

GPVI antagonist 3 (Compound 2) is a potential antagonist of Glycoprotein VI (GPVI). IC50 values of GPVI antagonist 3 are, respectively, 1.01 microM for collagen, 1.92 microM for CRP, 7.24 microM for convulxin and 51.74 microM for thrombin. Glycoprotein VI (GPVI) is a platelet major collagen receptor and a target for potent and safe antithrombotic research. GPVI antagonist 3 is a promising antiplatelet agent[1].

O=C1N(CCCO)C(C2=CC=C(OC)C=C2)C3=C1NN=C3C4=CC(C)=CC=C4O

12352200