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GPVI, Mouse (HEK293, His)

HY-P70180
MedChem Express
Protein IDB2RR15
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    MedChem Express
  • Product Name
    GPVI, Mouse (HEK293, His)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Estimated Purity
    97.34
  • Protein IDB2RR15
  • Protein Name
    Glycoprotein 6 (Platelet)
  • Scientific Description
    GPVI Protein is a platelet membrane protein with a molecular weight of ~62 kDa that is a physiological collagen receptor. GPVI is present as a complex with the homodimeric Fc receptor y-chain. GPVI must form such a dimeric complex to exhibit high affinity binding to collagen. The GPVI-induced activation mechanism is initiated by tyrosine phosphorylation of the immunoreceptor tyrosine-based activation motif (ITAM) of the FcR gamma-chain, and then this signal is transduced to many related proteins, mainly by tyrosine phosphorylation. Interaction of platelets with collagen via the receptor GPVI results in platelet activation and adhesion[1][2][3]. GPVI Protein, Mouse (HEK293, His) is the recombinant mouse-derived GPVI protein, expressed by HEK293 , with C-6*His labeled tag.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352202