ProductsBack/GPX2 antibody [C1C3]

GPX2 antibody [C1C3]

Name: GPX2 antibody [C1C3]
SKU: GTX100292_G10
Availability: BackOrder

GTX100292

ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetGPX2

Overview

Supplier
GeneTex
Product Name
GPX2 antibody [C1C3]
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:10000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1.07 mg/ml
Conjugate
Unconjugated
Gene ID2877
Target name
GPX2
Target description
glutathione peroxidase 2
Target synonyms
gastrointestinal glutathione peroxidase; GI-GPx; glutathione peroxidase 2; glutathione peroxidase 2 (gastrointestinal); glutathione peroxidase-related protein 2; GPRP; GPRP-2; GPx-2; GPx-GI; GSHPx-2; GSHPX-GI; selenoprotein GPX2
Host
Rabbit
Isotype
IgG
Protein IDP18283
Protein Name
Glutathione peroxidase 2
Scientific Description
This gene is a member of the glutathione peroxidase family and encodes a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. Studies in knockout mice indicate that mRNA expression levels respond to luminal microflora, suggesting a role of the ileal glutathione peroxidases in preventing inflammation in the GI tract. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Immunohistochemical Expression of Glutathione Peroxidase-2 (Gpx-2) and Its Clinical Relevance in Colon Adenocarcinoma Patients.
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Role of oncogene PIM-1 in the development and progression of papillary thyroid carcinoma: Involvement of oxidative stress. Wen QL et al., 2021 Mar 1, Mol Cell Endocrinol
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Mild Oxidative Stress Reduces NRF2 SUMOylation to Promote Kras/Lkb1/Keap1 Mutant Lung Adenocarcinoma Cell Migration and Invasion. Xu J et al., 2020, Oxid Med Cell Longev
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The nuclear hypoxia-regulated NLUCAT1 long non-coding RNA contributes to an aggressive phenotype in lung adenocarcinoma through regulation of oxidative stress. Moreno Leon L et al., 2019 Nov, Oncogene
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Caffeic acid and resveratrol ameliorate cellular damage in cell and Drosophila models of spinocerebellar ataxia type 3 through upregulation of Nrf2 pathway. Wu YL et al., 2018 Feb 1, Free Radic Biol Med
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Dietary selenium protects adiponectin knockout mice against chronic inflammation induced colon cancer. Saxena A et al., 2017 Apr 3, Cancer Biol Ther
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Glutathione-dependent and -independent oxidative stress-control mechanisms distinguish normal human mammary epithelial cell subsets. Kannan N et al., 2014 May 27, Proc Natl Acad Sci U S A
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