GPX2 antibody [C1C3]
GTX100292
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetGPX2
Overview
- SupplierGeneTex
- Product NameGPX2 antibody [C1C3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:10000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.07 mg/ml
- ConjugateUnconjugated
- Gene ID2877
- Target nameGPX2
- Target descriptionglutathione peroxidase 2
- Target synonymsGI-GPx, GPRP, GPRP-2, GPx-2, GPx-GI, GSHPX-GI, GSHPx-2, glutathione peroxidase 2, gastrointestinal glutathione peroxidase, glutathione peroxidase 2 (gastrointestinal), glutathione peroxidase-related protein 2, phospholipid hydroperoxide glutathione peroxidase GPX2, selenoprotein GPX2
- HostRabbit
- IsotypeIgG
- Protein IDP18283
- Protein NameGlutathione peroxidase 2
- Scientific DescriptionThis gene is a member of the glutathione peroxidase family and encodes a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. Studies in knockout mice indicate that mRNA expression levels respond to luminal microflora, suggesting a role of the ileal glutathione peroxidases in preventing inflammation in the GI tract. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Brzozowa-Zasada M, Ianaro A, Piecuch A, et al. Immunohistochemical Expression of Glutathione Peroxidase-2 (Gpx-2) and Its Clinical Relevance in Colon Adenocarcinoma Patients. Int J Mol Sci. 2023,24(19). doi: 10.3390/ijms241914650Read this paper
- Wen QL, Yi HQ, Yang K, et al. Role of oncogene PIM-1 in the development and progression of papillary thyroid carcinoma: Involvement of oxidative stress. Mol Cell Endocrinol. 2021,523:111144. doi: 10.1016/j.mce.2020.111144Read this paper
- Xu J, Guo H, Xing Z, et al. Mild Oxidative Stress Reduces NRF2 SUMOylation to Promote Kras/Lkb1/Keap1 Mutant Lung Adenocarcinoma Cell Migration and Invasion. Oxid Med Cell Longev. 2020,2020:6240125. doi: 10.1155/2020/6240125Read this paper
- Moreno Leon L, Gautier M, Allan R, et al. The nuclear hypoxia-regulated NLUCAT1 long non-coding RNA contributes to an aggressive phenotype in lung adenocarcinoma through regulation of oxidative stress. Oncogene. 2019,38(46):7146-7165. doi: 10.1038/s41388-019-0935-yRead this paper
- Wu YL, Chang JC, Lin WY, et al. Caffeic acid and resveratrol ameliorate cellular damage in cell and Drosophila models of spinocerebellar ataxia type 3 through upregulation of Nrf2 pathway. Free Radic Biol Med. 2018,115:309-317. doi: 10.1016/j.freeradbiomed.2017.12.011Read this paper
- Saxena A, Fayad R, Kaur K, et al. Dietary selenium protects adiponectin knockout mice against chronic inflammation induced colon cancer. Cancer Biol Ther. 2017,18(4):257-267. doi: 10.1080/15384047.2016.1276130Read this paper
- Kannan N, Nguyen LV, Makarem M, et al. Glutathione-dependent and -independent oxidative stress-control mechanisms distinguish normal human mammary epithelial cell subsets. Proc Natl Acad Sci U S A. 2014,111(21):7789-94. doi: 10.1073/pnas.1403813111Read this paper
Datasheet
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