GPX4-IN-13

MedChem Express

GPX4-IN-13

9

Research Use Only

C23H15NO3

353.37

GPX4-IN-13 (compound 16) is a GPX4 inhibitor with anticancer activity. GPX4-IN-13 reduces thyroid cell proliferation and induces ferroptosis by inhibiting the expression level of GPX4. GPX4-IN-13 inhibits the growth of three thyroid cancer cell lines: N-thy-ori-3-1 (IC50=8.39 microM), MDA-T32 (IC50=10.28 microM) and MDA-T41 (IC50=8.18 microM)[1].

O=C(C1=CC=C(C=C1)C#N)/C=C/C(C=CC=C2)=C2OC3=C(C=CC=C3)C=O

41115811