GRAF antibody, C-term

GeneTex

GRAF antibody, C-term

7

WB: 0.3-1microg/ml. IHC-P: 3.75microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.50 mg/ml

Unconjugated

ARHGAP26

Rho GTPase activating protein 26

GRAF, GRAF1, OPHN1L, OPHN1L1, rho GTPase-activating protein 26, GTPase regulator associated with focal adhesion kinase pp125(FAK), oligophrenin-1-like protein

Goat

IgG

Rho GTPase-activating protein 26

Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017]

Human

-20°C or -80°C,2°C to 8°C

12352203