Grancalcin antibody [N1C3]

GeneTex

Grancalcin antibody [N1C3]

9

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

0.99 mg/ml

Unconjugated

GCA

grancalcin

GCL; grancalcin; grancalcin, EF-hand calcium-binding protein; grancalcin, penta-EF-hand protein

Rabbit

IgG

Grancalcin

This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation. [provided by RefSeq]

Human

-20°C or -80°C,2°C to 8°C

12352203