Granzyme B antibody [14G13]

GeneTex

Granzyme B antibody [14G13]

9

WB: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Monoclonal

14G13

500 ug/ml

Unconjugated

Gzmb

granzyme B

AI553453; CCP; CCP1; CCP-1/C1; CCP-1/C11; Ctl; Ctla; Ctla1; Ctla-1; cytotoxic cell protease 1; fragmentin-2; granzyme B(G,H); GZB

Rat

IgG2

Granzyme B(G,H)

This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Mice lacking a functional copy of this gene exhibit impaired immune cell-mediated cytolysis. [provided by RefSeq, Sep 2016]

Mouse

-20°C or -80°C,2°C to 8°C

12352203