
WB analysis of human thymus lysate using GTX89994 GRAP antibody, C-term. Dilution : 0.3microg/ml Loading : 35microg protein in RIPA buffer
GRAP antibody, C-term
GTX89994
Overview
- SupplierGeneTex
- Product NameGRAP antibody, C-term
- Delivery Days Customer9
- Application Supplier NoteWB: 0.3-1microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID10750
- Target nameGRAP
- Target descriptionGRB2 related adaptor protein
- Target synonymsDFNB114; GRB2-related adapter protein; growth factor receptor-bound protein 2-related adaptor protein
- HostGoat
- IsotypeIgG
- Protein IDQ13588
- Protein NameGRB2-related adapter protein
- Scientific DescriptionThis gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway. [provided by RefSeq, Jul 2012]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203