Grb2, Human (His)

MedChem Express

Grb2, Human (His)

5

Research Use Only

97.60

GRB2

growth factor receptor bound protein 2

ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2, growth factor receptor-bound protein 2, HT027, SH2/SH3 adapter GRB2, abundant SRC homology, epidermal growth factor receptor-binding protein GRB2, epididymis secretory sperm binding protein, growth factor receptor-bound protein 3, protein Ash

Growth factor receptor-bound protein 2

Grb2, an adapter protein, crucially connects cell surface growth factor receptors to the Ras signaling pathway. Despite no direct binding to phosphorylated EGFR, Grb2 inhibits EGF-induced transactivation of a RAS-responsive element. It acts as a dominant negative relative to GRB2, suppressing proliferative signals and potentially initiating programmed cell death. Grb2 Protein, Human (His) is the recombinant human-derived Grb2 protein, expressed by E. coli , with C-6*His labeled tag.

-20°C

41116100

Human