GREM2 antibody [C1C3]
GTX108414
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Rat
TargetGREM2
Overview
- SupplierGeneTex
- Product NameGREM2 antibody [C1C3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.26 mg/ml
- ConjugateUnconjugated
- Gene ID64388
- Target nameGREM2
- Target descriptiongremlin 2, DAN family BMP antagonist
- Target synonymsCKTSF1B2; cysteine knot superfamily 1, BMP antagonist 2; DAN domain family member 3; DAND3; gremlin 2, cysteine knot superfamily, homolog; gremlin-2; PRDC; protein related to DAN and cerberus; STHAG9
- HostRabbit
- IsotypeIgG
- Protein IDQ9H772
- Protein NameGremlin-2
- Scientific DescriptionThis gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. [provided by RefSeq]
- ReactivityHuman, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Triosephosphate isomerase of Streptococcus pneumoniae is released extracellularly by autolysis and binds to host plasminogen to promote its activation. Hirayama S et al., 2022 Jun, FEBS Open BioRead more
- Gremlin 2 suppresses differentiation of stem/progenitor cells in the human skin. Kawagishi-Hotta M et al., 2021 Dec, Regen TherRead more
- Increase of gremlin 2 with age in human adipose-derived stromal/stem cells and its inhibitory effect on adipogenesis. Kawagishi-Hotta M et al., 2019 Dec, Regen TherRead more
- Coordinated Proliferation and Differentiation of Human-Induced Pluripotent Stem Cell-Derived Cardiac Progenitor Cells Depend on Bone Morphogenetic Protein Signaling Regulation by GREMLIN 2. Bylund JB et al., 2017 May 1, Stem Cells DevRead more
- Effects of gremlin-2 on the transition of primordial follicles during early folliculogenesis in the human ovary. Ikeda Y et al., 2016 Aug, Eur J Obstet Gynecol Reprod BiolRead more