GRIK5 antibody

GeneTex

GRIK5 antibody

9

This Grik5 antibody does not cross-react with Grik4.

WB: 0.5 - 2 microg/mL. IHC-P: 2.5 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

GRIK5

glutamate ionotropic receptor kainate type subunit 5

EAA2; excitatory amino acid receptor 2; GluK5; glutamate receptor ionotropic, kainate 5; glutamate receptor KA2; GRIK2; KA2; putative NMDtranscript(altDon_e2); putative NMDtranscript(del_e13-e15)

Rabbit

IgG

Glutamate receptor ionotropic, kainate 5

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik5, also known as kainate-preferring glutamate recptor subunit KA2, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Grik5 is highly homologous to the related ionotrophic glutamate receptor Grik4 (also known as KA1). Like Grik4, Grik5 does not form homomeric channels, but instead forms heteromers with Grik2. In Grik2- but not Grik1- mice, Grik5 surface expression is greatly reduced in neurons, indicating that Grik2/Grik5 heteromers are required for exit from the endoplasmic reticulum to the cell surface. This Grik5 antibody does not cross-react with Grik4.

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203