Western blot analysis of extract from T98G cells using NMDANR2B Subunit Antibody
Western blot analysis of extract from T98G cells using NMDANR2B Subunit Antibody
Grin2b Antibody
CSB-PA191146
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetGrin2b
Overview
- SupplierCusabio
- Product NameGrin2b Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID24410
- Target nameGrin2b
- Target descriptionglutamate ionotropic receptor NMDA type subunit 2B
- Target synonymsGluN2B; glutamate [NMDA] receptor subunit epsilon-2; glutamate receptor ionotropic, NMDA 2B; glutamate receptor, ionotropic, NMDA2B; glutamate receptor, ionotropic, N-methyl D-aspartate 2B; NMDAR2B; N-methyl D-aspartate receptor subtype 2B; NR2B
- HostRabbit
- IsotypeIgG
- Protein IDQ00960
- Protein NameGlutamate receptor ionotropic, NMDA 2B
- Scientific DescriptionNMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death Kornau H.C., Schenker L.T., Kennedy M.B., Seeburg P.H.Science 269:1737-1740(1995) Kurschner C., Mermelstein P.G., Holden W.T., Surmeier D.J.Mol. Cell. Neurosci. 11:161-172(1998)
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203