GRK5-IN-4 [2410794-89-5]
HY-150022
CAS Number2410794-89-5
Product group Chemicals
Molecular Weight483.52
Overview
- SupplierMedChem Express
- Product NameGRK5-IN-4 [2410794-89-5]
- Delivery Days Customer10
- CAS Number2410794-89-5
- CertificationResearch Use Only
- Molecular FormulaC26H25N7O3
- Molecular Weight483.52
- Scientific DescriptionGRK5-IN-4 (Compound 16d, CCG-265328) is a potent and and selective covalent GRK5 (G protein-coupled receptor kinase 5) inhibitor, with an IC50 of 1.1 microM. GRK5-IN-4 shows 90-fold selectivity over GRK2. GRK5-IN-4 can be used for heart failure research[1]. GRK5-IN-4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- SMILESO=C(NCC1=CC=C(C(OC)=C1)NC2=NC(NC3=C(C(NC)=O)C=CC=C3)=C4C=CNC4=N2)C#CC
- UNSPSC12131703