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GRP1 antibody [N3C3]

Research Use Only
GTX115211
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Zebra Fish
TargetCYTH3
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Overview

  • Supplier
    GeneTex
  • Product Name
    GRP1 antibody [N3C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.63 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID9265
  • Target name
    CYTH3
  • Target description
    cytohesin 3
  • Target synonyms
    ARF nucleotide-binding site opener 3; ARNO3; cytohesin-3; general receptor of phosphoinositides 1; GRP1; PH, SEC7 and coiled-coil domain-containing protein 3; pleckstrin homology, Sec7 and coiled-coil domains 3; PSCD3
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO43739
  • Protein Name
    Cytohesin-3
  • Scientific Description
    This gene encodes a member of the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. PSCD family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This encoded protein is involved in the control of Golgi structure and function, and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions, in addition to acting on ARF1. [provided by RefSeq]
  • Reactivity
    Human, Zebra Fish
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • An ARF6-Exportin-5 axis delivers pre-miRNA cargo to tumour microvesicles. Clancy JW et al., 2019 Jul, Nat Cell Biol
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