Grp78 antibody

GeneTex

Grp78 antibody

9

WB: 2 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

Hspa5

heat shock protein 5

78 kDa glucose-regulated protein; 78kD; AL022860; AU019543; B; baffl; baffled; binding-immunoglobulin protein; Bip; D2Wsu141; D2Wsu141e; D2Wsu17; D2Wsu17e; endoplasmic reticulum chaperone BiP; glucose regulated protein, 78 kDa; Grp; Grp78; GRP-78; heat shock 70 kDa protein 5; heat shock 70kD protein 5 (glucose-regulated protein, 78kD); heat shock protein 70 family protein 5; heat shock protein family A member 5; Hsce7; Hsce70; HSP70 family protein 5; immunoglobulin heavy chain-binding protein; mB; mBiP; Sez; Sez7; SEZ-7; XAP-1 antigen

Rabbit

IgG

Endoplasmic reticulum chaperone BiP

The 78 kDa glucose regulated protein/BiP (GRP78) belongs to the family of ~70 kDa heat shock proteins (HSP70). GRP78 is a resident protein of the endoplasmic reticulum (ER) and associates transiently with a variety of newly synthesized secretory and membrane proteins. GRP78 may also interact with mutant and misfolded proteins, marking them for degredation. The highly conserved sequence Lys-Asp-Glu-Leu (KDEL) is present at the C-terminus of GRP78 and other resident ER proteins including glucose regulated protein 94 (GRP94) and protein disulfide isomerase (PDI). The KDEL signal is recognized by the KDEL receptor and this interaction ensures recycling of escaped ER proteins back to the ER.

-20°C or -80°C,2°C to 8°C

12352203