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ProductsBack/GS-443902 trisodium [1355050-21-3]
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GS-443902 trisodium [1355050-21-3]

Research Use Only
T38761
TargetMol Chemicals
CAS Number1355050-21-3
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Product group Chemicals
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    GS-443902 trisodium [1355050-21-3]
  • Delivery Days Customer
    16
  • CAS Number
    1355050-21-3
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    GS-443902 trisodium
  • Scientific Description
    GS-443902 trisodium (GS-441524 triphosphate trisodium), the active triphosphate metabolite of Remdesivir (GS-5734), serves as a potent inhibitor of viral RNA-dependent RNA-polymerases (RdRp), displaying inhibitory concentrations (IC50) of 1.1 microM for RSV RdRp and 5 microM for HCV RdRp.
  • Shelf life instruction
    3 years
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Siegel D, et al. Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses. Med Chem. 2017 Mar 9;60(5):1648-1661.
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