GS-6201

MedChem Express

GS-6201 [752222-83-6]

10

752222-83-6

99.72

C21H21F3N6O2

446.43

GS-6201 (CVT-6883) is a selective adenosine A2B receptor antagonist. GS-6201 displays high affinity and selectivity for the human adenosine A2B receptors ( K i =22 nM) [1] . GS-6201 reduces caspase-1 activity in the heart, and attenuates cardiac remodeling after acute myocardial infarction (AMI) in the mouse [2] . GS-62013 attenuates the airway reactivity induced by NECA, AMP, or allergen in sensitized mice [3] .

O=C(N1CCC)N(CC)C2=C(N=C(C3=CN(CC4=CC=CC(C(F)(F)F)=C4)N=C3)N2)C1=O

-20°C

12352200