Western Blot Positive WB detected in: HGC27 whole cell lysate All lanes: GSDMA antibody at 3.85microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 50 kDa Observed band size: 50 kDa
Western Blot Positive WB detected in: HGC27 whole cell lysate All lanes: GSDMA antibody at 3.85microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 50 kDa Observed band size: 50 kDa
GSDMA Antibody
CSB-PA850415LA01HU
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetGSDMA
Overview
- SupplierCusabio
- Product NameGSDMA Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID284110
- Target nameGSDMA
- Target descriptiongasdermin A
- Target synonymsFKSG9; gasdermin-1; gasdermin-A; GSDM; GSDM1
- HostRabbit
- IsotypeIgG
- Protein IDQ96QA5
- Protein NameGasdermin-A
- Scientific DescriptionMay promote pyroptosis (Probable). Upon cleavage in vitro of genetically engineered GSDMA, the released N-terminal moiety binds to some types of lipids, such as possibly phosphatidylinositol (4,5)-bisphosphate. Homooligomerizes within the membrane and forms pores of 10 -15 nanometers (nm) of inner diameter, triggering cell death. Also binds to bacterial and mitochondrial lipids, including cardiolipin, and exhibits bactericidal activity (PubMed:27281216). The physiological relevance of these observations is unknown (Probable).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203