GSK-1070916

MedChem Express

GSK-1070916 [942918-07-2]

10

942918-07-2

Research Use Only

99.55

C30H33N7O

507.63

GSK-1070916 is a potent and selective ATP-competitive inhibitor of aurora B and aurora C with K i s of 0.38 and 1.5 nM, respectively, and is >250- fold selective over Aurora A.

O=C(NC1=CC=C(C2=NN(C=C2C3=C4C(NC(C5=CC=CC(CN(C)C)=C5)=C4)=NC=C3)CC)C=C1)N(C)C

-20°C,2°C to 8°C

12352200