GSK-3beta inhibitor 15

MedChem Express

GSK-3beta inhibitor 15

14

Research Use Only

C17H16N6OS

352.41

GSK-3beta inhibitor 15 (Compound 54) is a GSK-3beta inhibitor (IC50: 3.4 nM). GSK-3beta inhibitor 15 inhibits Abeta1-42-induced GSK-3beta and tau protein phosphorylation. GSK-3beta inhibitor 15 inhibits LPS-induced iNOS expression. GSK-3beta inhibitor 15 has neuroprotective effects on Abeta1-42-induced neurotoxicity. GSK-3beta inhibitor 15 can be used for research of Alzheimers disease (AD)[1].

O=C(CCN1N=CC(C)=C1)NC2=NNC3=C2SC(C4=CN=CC=C4)=C3

12131703