GSK-843

MedChem Express

GSK-843 [1601496-05-2]

5

1601496-05-2

Research Use Only

99.18

C19H15N5S2

377.49

GSK-843 (GSK843) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds RIP3 kinase domain with an IC 50 of 8.6 nM, and inhibits kinase activity with an IC 50 of 6.5 nM. GSK-843 can be used for the research of inflammation [1] [2] .

NC1=NC=C(C2=CC(C)=NN2C)C3=C1C(C4=CC=C(SC=N5)C5=C4)=CS3

-20°C

12352200