GSK-872
HY-101872
CAS Number1346546-69-7
Product group Chemicals
Estimated Purity99.96
Molecular Weight383.49
Overview
- SupplierMedChem Express
- Product NameGSK-872 [1346546-69-7]
- Delivery Days Customer10
- CAS Number1346546-69-7
- CertificationResearch Use Only
- Estimated Purity99.96
- Molecular FormulaC19H17N3O2S2
- Molecular Weight383.49
- Scientific DescriptionGSK-872 is a RIPK3 inhibitor, which binds RIP3 kinase domain with an IC 50 of 1.8 nM, and inhibits kinase activity with an IC 50 of 1.3 nM. GSK-872 decreases the RIPK3-mediated necroptosis and subsequent cytoplasmic translocation and expression of HMGB1, as well as ameliorates brain edema and neurological deficits in early brain injury [1] [2] [3] .
- SMILESO=S(C1=CC=C2N=CC=C(C2=C1)NC3=CC=C4SC=NC4=C3)(C(C)C)=O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200