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GSK2194069

HY-12325
MedChem Express
CAS Number1332331-08-4
Product group Chemicals
Estimated Purity99.80
Molecular Weight428.48
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Overview

  • Supplier
    MedChem Express
  • Product Name
    GSK2194069 [1332331-08-4]
  • Delivery Days Customer
    10
  • CAS Number
    1332331-08-4
  • Certification
    Research Use Only
  • Estimated Purity
    99.80
  • Molecular Formula
    C25H24N4O3
  • Molecular Weight
    428.48
  • Scientific Description
    GSK2194069 is a potent inhibitor of beta-ketoyl reductase (KR) of fatty acid synthase (FASN), with an IC50 value of 7.7 nM. GSK2194069 shows specifically inhibitory effect on FAS expressing cancer cells, by acting potent efficacy on acetoacetyl-CoA, NADPH with IC50 or Ki values of 4.8 nM and 5.6 nM, respectively[1][2][3].
  • SMILES
    O=C(N1C[C@H](CC2=NNC(N2C3=CC=C(C4=CC=C(OC=C5)C5=C4)C=C3)=O)CC1)C6CC6
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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