GSK223 [899758-61-3]
HY-118316
CAS Number899758-61-3
Product group Chemicals
Molecular Weight443.51
Overview
- SupplierMedChem Express
- Product NameGSK223 [899758-61-3]
- Delivery Days Customer5
- CAS Number899758-61-3
- CertificationResearch Use Only
- Molecular FormulaC21H18FN3O3S2
- Molecular Weight443.51
- Scientific DescriptionGSK223 is a quinazolinone NOD1 pathway inhibitor with potential anti-inflammatory activity. GSK223 can selectively inhibit IL-8 release under iE-DAP stimulation without affecting IL-8 secretion caused by TNF receptor, TLR2 or NOD2 agonists. GSK223 does not directly inhibit RIP2 kinase activity.
- SMILESO=S(C1=CC=C(S1)CC)(NC2=CC(N3C(C)=NC4=C(C3=O)C=CC=C4)=CC=C2F)=O
- UNSPSC12352200