GSK2245035 [1207629-49-9]

MedChem Express

GSK2245035 [1207629-49-9]

9

1207629-49-9

Research Use Only

99.85

C20H34N6O2

390.52

GSK2245035 is a highly potent and selective intranasal Toll-Like receptor 7 (TLR7) agonist with preferential Type-1 interferon (IFN)-stimulating properties. GSK2245035 has pEC50s of 9.3 and 6.5 for IFNalpha and TFNalpha. GSK2245035 effectively suppresses allergen-induced Th2 cytokine production in human peripheral blood cell cultures. GSK2245035 is used for asthma[1].

O=C1NC2=C(N=C(N=C2N1CCCCCN3CCCCC3)O[C@H](CCC)C)N

-20°C,2°C to 8°C

12352200