GSK2245035 (maleate) [1325212-97-2]

MedChem Express

GSK2245035 (maleate) [1325212-97-2]

9

1325212-97-2

Research Use Only

C24H38N6O6

506.60

GSK2245035 maleate is a highly potent and selective intranasal Toll-Like receptor 7 (TLR7) agonist with preferential Type-1 interferon (IFN)-stimulating properties. GSK2245035 maleate has pEC50s of 9.3 and 6.5 for IFNalpha and TFNalpha. GSK2245035 maleate effectively suppresses allergen-induced Th2 cytokine production in human peripheral blood cell cultures. GSK2245035 maleate is used for asthma[1].

OC(/C=C\C(O)=O)=O.O=C(N(C1=NC(O[C@@H](C)CCC)=N2)CCCCCN3CCCCC3)NC1=C2N

12352200